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signal intensity heat map  (GraphPad Software Inc)


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    GraphPad Software Inc signal intensity heat map
    Inhibition of eEF2K synchronizes neuronal activity pattern in primary hippocampal cell cultures. (A–C) Images, traces, and <t>heat</t> <t>maps</t> in the figure represent data from one representative experiment before and during drug application. (A) The time points for the representative frames of a fluorescence image sequence are indicated under the traces in (B) with arrows and letters or numbers. Dashed circles indicate representative neurons (14, 9, and 13). Scale bar, 100 μm. (B) The time courses of changes in fluorescence <t>intensity</t> for three neurons (color-coded throughout the figure) before and during drug application are presented. Vertical scale bar: 2000 (F-F 0 /F 0 ) and horizontal bar: 5 s. (C) The degree of synchronized spike activity of neurons to each other are represented by a Pearson’s correlation based hierarchical clustering matrices. (D) Theoretical Gaussian fits for the frequency distribution histograms of Pearson’s correlation coefficients were created for all neuronal pairs of three cultures analyzed before and during drug application. (E) The bar graph summarizes the mean values of correlation coefficient (CC) matrices. The brackets and asterisks indicate the degree of significant difference ( ∗ p < 0.05) of the coefficients before (0.29 ± 0.11) and after drug application (0.67 ± 0.08).
    Signal Intensity Heat Map, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/signal+intensity+heat+map/pmc05078695-240-3-16?v=GraphPad+Software+Inc
    Average 90 stars, based on 1 article reviews
    signal intensity heat map - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Potentiation of Schaffer-Collateral CA1 Synaptic Transmission by eEF2K and p38 MAPK Mediated Mechanisms"

    Article Title: Potentiation of Schaffer-Collateral CA1 Synaptic Transmission by eEF2K and p38 MAPK Mediated Mechanisms

    Journal: Frontiers in Cellular Neuroscience

    doi: 10.3389/fncel.2016.00247

    Inhibition of eEF2K synchronizes neuronal activity pattern in primary hippocampal cell cultures. (A–C) Images, traces, and heat maps in the figure represent data from one representative experiment before and during drug application. (A) The time points for the representative frames of a fluorescence image sequence are indicated under the traces in (B) with arrows and letters or numbers. Dashed circles indicate representative neurons (14, 9, and 13). Scale bar, 100 μm. (B) The time courses of changes in fluorescence intensity for three neurons (color-coded throughout the figure) before and during drug application are presented. Vertical scale bar: 2000 (F-F 0 /F 0 ) and horizontal bar: 5 s. (C) The degree of synchronized spike activity of neurons to each other are represented by a Pearson’s correlation based hierarchical clustering matrices. (D) Theoretical Gaussian fits for the frequency distribution histograms of Pearson’s correlation coefficients were created for all neuronal pairs of three cultures analyzed before and during drug application. (E) The bar graph summarizes the mean values of correlation coefficient (CC) matrices. The brackets and asterisks indicate the degree of significant difference ( ∗ p < 0.05) of the coefficients before (0.29 ± 0.11) and after drug application (0.67 ± 0.08).
    Figure Legend Snippet: Inhibition of eEF2K synchronizes neuronal activity pattern in primary hippocampal cell cultures. (A–C) Images, traces, and heat maps in the figure represent data from one representative experiment before and during drug application. (A) The time points for the representative frames of a fluorescence image sequence are indicated under the traces in (B) with arrows and letters or numbers. Dashed circles indicate representative neurons (14, 9, and 13). Scale bar, 100 μm. (B) The time courses of changes in fluorescence intensity for three neurons (color-coded throughout the figure) before and during drug application are presented. Vertical scale bar: 2000 (F-F 0 /F 0 ) and horizontal bar: 5 s. (C) The degree of synchronized spike activity of neurons to each other are represented by a Pearson’s correlation based hierarchical clustering matrices. (D) Theoretical Gaussian fits for the frequency distribution histograms of Pearson’s correlation coefficients were created for all neuronal pairs of three cultures analyzed before and during drug application. (E) The bar graph summarizes the mean values of correlation coefficient (CC) matrices. The brackets and asterisks indicate the degree of significant difference ( ∗ p < 0.05) of the coefficients before (0.29 ± 0.11) and after drug application (0.67 ± 0.08).

    Techniques Used: Inhibition, Activity Assay, Fluorescence, Sequencing



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    signal intensity heat map  (GraphPad Software Inc)
    90
    GraphPad Software Inc signal intensity heat map
    Inhibition of eEF2K synchronizes neuronal activity pattern in primary hippocampal cell cultures. (A–C) Images, traces, and <t>heat</t> <t>maps</t> in the figure represent data from one representative experiment before and during drug application. (A) The time points for the representative frames of a fluorescence image sequence are indicated under the traces in (B) with arrows and letters or numbers. Dashed circles indicate representative neurons (14, 9, and 13). Scale bar, 100 μm. (B) The time courses of changes in fluorescence <t>intensity</t> for three neurons (color-coded throughout the figure) before and during drug application are presented. Vertical scale bar: 2000 (F-F 0 /F 0 ) and horizontal bar: 5 s. (C) The degree of synchronized spike activity of neurons to each other are represented by a Pearson’s correlation based hierarchical clustering matrices. (D) Theoretical Gaussian fits for the frequency distribution histograms of Pearson’s correlation coefficients were created for all neuronal pairs of three cultures analyzed before and during drug application. (E) The bar graph summarizes the mean values of correlation coefficient (CC) matrices. The brackets and asterisks indicate the degree of significant difference ( ∗ p < 0.05) of the coefficients before (0.29 ± 0.11) and after drug application (0.67 ± 0.08).
    Signal Intensity Heat Map, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/signal+intensity+heat+map/pmc05078695-240-3-16?v=GraphPad+Software+Inc
    Average 90 stars, based on 1 article reviews
    signal intensity heat map - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Inhibition of eEF2K synchronizes neuronal activity pattern in primary hippocampal cell cultures. (A–C) Images, traces, and heat maps in the figure represent data from one representative experiment before and during drug application. (A) The time points for the representative frames of a fluorescence image sequence are indicated under the traces in (B) with arrows and letters or numbers. Dashed circles indicate representative neurons (14, 9, and 13). Scale bar, 100 μm. (B) The time courses of changes in fluorescence intensity for three neurons (color-coded throughout the figure) before and during drug application are presented. Vertical scale bar: 2000 (F-F 0 /F 0 ) and horizontal bar: 5 s. (C) The degree of synchronized spike activity of neurons to each other are represented by a Pearson’s correlation based hierarchical clustering matrices. (D) Theoretical Gaussian fits for the frequency distribution histograms of Pearson’s correlation coefficients were created for all neuronal pairs of three cultures analyzed before and during drug application. (E) The bar graph summarizes the mean values of correlation coefficient (CC) matrices. The brackets and asterisks indicate the degree of significant difference ( ∗ p < 0.05) of the coefficients before (0.29 ± 0.11) and after drug application (0.67 ± 0.08).

    Journal: Frontiers in Cellular Neuroscience

    Article Title: Potentiation of Schaffer-Collateral CA1 Synaptic Transmission by eEF2K and p38 MAPK Mediated Mechanisms

    doi: 10.3389/fncel.2016.00247

    Figure Lengend Snippet: Inhibition of eEF2K synchronizes neuronal activity pattern in primary hippocampal cell cultures. (A–C) Images, traces, and heat maps in the figure represent data from one representative experiment before and during drug application. (A) The time points for the representative frames of a fluorescence image sequence are indicated under the traces in (B) with arrows and letters or numbers. Dashed circles indicate representative neurons (14, 9, and 13). Scale bar, 100 μm. (B) The time courses of changes in fluorescence intensity for three neurons (color-coded throughout the figure) before and during drug application are presented. Vertical scale bar: 2000 (F-F 0 /F 0 ) and horizontal bar: 5 s. (C) The degree of synchronized spike activity of neurons to each other are represented by a Pearson’s correlation based hierarchical clustering matrices. (D) Theoretical Gaussian fits for the frequency distribution histograms of Pearson’s correlation coefficients were created for all neuronal pairs of three cultures analyzed before and during drug application. (E) The bar graph summarizes the mean values of correlation coefficient (CC) matrices. The brackets and asterisks indicate the degree of significant difference ( ∗ p < 0.05) of the coefficients before (0.29 ± 0.11) and after drug application (0.67 ± 0.08).

    Article Snippet: To generate a signal intensity heat map and analog traces, the values were further normalized in GraphPad by the average gray values of the initial 2 s of the sequence (F 0 ).

    Techniques: Inhibition, Activity Assay, Fluorescence, Sequencing